The escalating threat of multidrug-resistant bacteria poses a significant challenge to hospitals worldwide. Critically ill patients are particularly vulnerable to these infections, making the selection and dosing of antimicrobials a complex and crucial task.
At Bologna University Hospital in Italy, Professor Federico Pea and his team have developed a comprehensive and interdisciplinary program to tailor antibiotic therapy. This approach is based on accurate Minimum Inhibitory Concentration (MIC) values, real-time therapeutic drug monitoring (TDM) data, and pharmacokinetic/pharmacodynamic (PK/PD) parameters.